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99.9% Long Acting Local Anesthetic Drugs Pain Reliver Raw Powder Prilocaine CAS 721-50-6 For Analgesic

Categories Local Anesthetic Powder
Brand Name: TINGYI
Model Number: CAS: 721-50-6
Certification: GMP , ISO 9001:2008
Place of Origin: CHINA
MOQ: 10g
Price: Contact Us
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 3000KG/Month
Delivery Time: Usually within 7 work days
Packaging Details: Stealth and discreet packaging
CAS: 721-50-6
Synonyms: Astra 1512 ; Astra 1515
MF: C13H20N2O
MW: 220.31
EINECS: 211-957-0
Appearance: White powder
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    99.9% Long Acting Local Anesthetic Drugs Pain Reliver Raw Powder Prilocaine CAS 721-50-6 For Analgesic

    Product Name: Prilocaine

    Quick Detail:


    Product name

    Prilocaine

    Synonym

    Astra 1512; Astra 1515;astra1512

    CAS NO

    721-50-6

    Molecular Formula

    C13H20N2O

    Molecular weight

    220.31

    EINECS

    211-957-0

    Purity

    98%

    Appearance

    White powder

    Boiling Point

    37-38°

    Certification

    ISO9001

    Suitable for
    adult, edlerly
    Standard

    Enterprise Standard

    Usage

    Local anesthetic; Mainly used in mucosa anesthetic.

    Packing

    Discreet packing ways as your requirement, 100% go through.

    Storage

    Store in cool and dry area and keep away from direct sunlight.


    Description:


    Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren.
    In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).
    Prilocaine belongs to amide local anesthetic drug with its anesthesia intensity and speed being similar as lidocaine but with a longer duration period and weaker effect on vasodilation. It has a lower toxicity than lidocaine. It is clinically for local anesthesia, especially suitable for treating patients who are not allowed to use adrenaline.


    Anesthesia, local- Proparacaine and tetracaine are indicated to produce local anesthesia of short duration for ophthalmic procedures including measurement of intraocular pressure, removal of foreign bodies and sutures, and conjunctival and corneal scraping in diagnosis and gonioscopy.

    prilocaine topical cream is used on the skin or in the genital area to cause numbness or loss of feeling before certain medical procedures. It is used to prevent pain caused by an injection, the drawing of blood from a vein, or minor surgeries such as removing warts. This medicine contains a mixture of two topical local anesthetics. It deadens the nerve endings in the skin. Relieving pain of normal intact skin and numbing skin to pain from injections and other medical procedures. prilocaine cream is a local anesthetic. It works by blocking nerves from transmitting painful impulses to the brain Prilocaine Hydrochloride Injection, USP, 4% is a sterile, non pyrogenic isotonic solution that contains a local anesthetic agent and is administered parenterally by injection. See indications and usage for specific uses.


    Applications:


    Information derived from diverse formulations, concentrations and usages reveals that prilocaine is completely absorbed following parenteral administration, its rate of absorption depending, for example, upon such factors as the site of administration and the presence or absence of a vasoconstrictor agent. Prilocaine is metabolized in both the liver and the kidney and excreted via the kidney. It is not metabolized by plasma esterases. Hydrolysis of prilocaine by amidases yields ortho-toluidine and N-proylalanine..
    Lidocaine and Prilocaine cream is a eutectic mixture of lidocaine 2.5% and prilocaine 2.5% formulated as an oil in water emulsion. In this eutectic mixture, both anesthetics are liquid at room temperature and the penetration and subsequent systemic absorption of both prilocaine and lidocaine are enhanced over that which would be seen if each component in crystalline form was applied separately as a 2.5% topical cream.

    Prilocaine topical is a local anesthetic (numbing medication). It works by blocking nerve signals in your body. Prilocaine topical is used to numb the skin, or surfaces of the penis or vagina, in preparation for a medical procedure or to lessen the pain of inserting a medical instrument such as a tube or speculum.
    Proparacaine hydrochloride and tetracaine are also indicated to produce local anesthesia prior to surgical procedures such as cataract extraction and pterygium excision, usually as an adjunct to locally injected anesthetics. Ophthalmic solutions used for intraocular procedures should be preservative-free. Preservatives may cause damage to the corneal epithelium if a significant quantity of solutionenters the eye through the incision.


    Prilocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action.
    Excessive blood levels may cause changes in cardiac output, total peripheral resistance, and mean arterial pressure. These changes may be attributable to a direct depressant effect of the local anesthetic agent on various components of the cardiovascular system. Prilocaine crosses the blood-brain and placental barriers, presumably by passive diffusion. Factors such as acidosis and the use of CNS stimulants and depressants affect the CNS levels of prilocaine required to produce overt systemic effects. In the rhesus monkey, arterial blood levels of 20 mg/mL have been shown to be the threshold for convulsive activity.



    COA:



    Product Name

    Prilocaine

    Alias

    2-(propylamino)-o-propionotoluidid, xylonest

    Assay (%)

    ≥ 99.00

    Odor

    Characteristic

    Color

    White crystalline powder

    Melting Point

    /

    Molecular Formula

    C13H20N2O

    Molecular Weight

    220.31

    Cas No.

    721-50-6

    EINECS No.

    211-957-0

    Standard

    USP/BP

    Main Functions

    Local anesthetic.

    Applications

    Pharmaceutical fields

    Package

    Aluminum foil bag inside+ Carton box outside;1kg/bag,25kg/drum;

    Shelf Life

    36 months

    Storage

    Store in sealed containers at cool & dry place. Keep away from light, moisture, pest infestation.

    Usage and Dosage:


    Infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to 1.5 hours.


    Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours.


    Epidural anesthesia: use10 to 30 mL of 1.5% ~ 1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600 mg.


    OUR ADWANTAGE:


    1, High quality with competitive price:
    1) Standard: U.S Standard
    2) All Purity≥99.8%
    3) We are manufacturer and can provide high quality products with factory price.


    2, Fast and safe delivery
    1) Parcel can be sent out within 8 hours after payment. Tracking number available
    2) Secure and discreet shipment. Various transportation methods for your choice.
    3) Customs pass rate ≥99.8%
    4)We provide re-ship policy.
    5) We have warehouse in Australia, Canada and England, we have large amounts of stock in the warehouse, can ship to you directly from our foreign warehouse!
    3, We have clients throughout the world.
    1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
    2) Meeting customers's requirement is our responsibility.
    3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.


    The Related Local Anesthetic Products:


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    LidocaineCAS:137-58-6
    Dibucaine hydrochlorideCAS:61-12-1
    PrilocaineCAS:721-50-6
    Propitocaine hydrochlorideCAS:1786-81-8
    Proparacaine hydrochlorideCAS:5875-06-9
    Lidocaine hydrochlorideCAS:73-78-9
    Articaine hydrochlorideCAS:23964-57-0
    Levobupivacaine hydrochlorideCAS:27262-48-2
    Ropivacaine hydrochlorideCAS:132112-35-7
    BupivacaineCAS:2180-92-9
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    Pramoxine HydrochlorideCAS:637-58-1
    Procaine HClCAS:51-05-8

    Quality 99.9% Long Acting Local Anesthetic Drugs Pain Reliver Raw Powder Prilocaine CAS 721-50-6 For Analgesic for sale
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